Lacosam 50mg (lacosamide) works by stabilizing abnormal electrical activity in the brain, which helps to prevent or reduce seizures. While the exact mechanism of action of lacosamide is not fully understood, it is believed to involve multiple effects on neuronal activity.
Lacosamide is known to selectively enhance the slow inactivation of sodium channels in the brain. By promoting slow inactivation, it helps to limit the excessive firing of neurons and reduce the spread of abnormal electrical signals that can lead to seizures. This action is thought to have an antiepileptic effect, particularly in the case of partial-onset seizures.
In addition to its effects on sodium channels, lacosamide may also interact with other targets in the brain, such as calcium channels and synaptic vesicle protein 2A (SV2A). These interactions may further contribute to its antiepileptic effects, although their precise mechanisms are not fully elucidated.
By modulating electrical activity in the brain, lacosamide helps to normalize neuronal function and prevent the occurrence or spread of seizures. This can result in a reduction in seizure frequency and severity, providing better seizure control for individuals with epilepsy.
It's important to note that the exact way lacosamide works and its specific effects can vary between individuals and may depend on the underlying cause and type of seizures. The use of lacosamide is typically determined by a healthcare professional who will consider various factors and tailor the treatment plan based on the individual's specific condition.