Tresiba (insulin degludec) is generally well-tolerated, but like all medications, it can have side effects. Not everyone will experience these side effects, and some people may experience them to varying degrees of severity. Common side effects of Tresiba include:
Hypoglycemia: Low blood sugar (hypoglycemia) is the most common side effect of insulin therapy, including Tresiba. Symptoms of hypoglycemia can include shakiness, sweating, rapid heartbeat, confusion, dizziness, and headache.
Injection Site Reactions: Some individuals may experience redness, swelling, or itching at the injection site. These reactions are typically mild and tend to resolve on their own.
Weight Gain: Insulin therapy can lead to weight gain for some people. This is because insulin promotes the storage of glucose and can lead to increased fat storage.
Allergic Reactions: Although rare, some people may have an allergic reaction to Tresiba. Signs of an allergic reaction can include itching, rash, swelling, severe dizziness, and difficulty breathing.
Lipodystrophy: Prolonged use of insulin at the same injection site may lead to fat tissue changes, such as thickening or thinning of the skin. This is known as lipodystrophy.
Fluid Retention: Insulin therapy can sometimes lead to fluid retention, which may result in swelling in the hands or feet.